Mating With Denisovans May Have Left Us Depressed

It seems like only a few years ago we learned that modern humans carry around genes we inherited from our ancestors interbreeding with Neanderthals. Now there is evidence that we also have genes that originated with another extinct human species, the Denisovans. Actual fossil evidence of Denisovans is scant, but we have enough genetic material to trace back some of our modern human genes to them.

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Denisovans evolved to survive in the mountains of Asia, and certain genes made them more adaptable to those conditions. One genetic variant allowed them to thrive in high altitudes, and that variant now only survives in Tibetans. But another genetic adaptation is now found in all populations outside of Africa. A gene called SLC30A9 regulates how zinc moves within a cell, which can have many effects. A mutation in that gene among Denisovans may have helped them adapt to cold climates. But it also appears to have left the rest of us predisposed to depression and other mental health problems. Read more about this research at Neoscope. -via Damn Interesting

(Image credit: Vincent van Gogh)

Source: neatorama

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